DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6592 and HABP2

DIOPT Version :9

Sequence 1:NP_648016.1 Gene:CG6592 / 38687 FlyBaseID:FBgn0035669 Length:438 Species:Drosophila melanogaster
Sequence 2:NP_004123.1 Gene:HABP2 / 3026 HGNCID:4798 Length:560 Species:Homo sapiens


Alignment Length:315 Identity:82/315 - (26%)
Similarity:129/315 - (40%) Gaps:78/315 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 ALSEEDDREPLVL-----NLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVG------MLL 142
            |..||...||...     :...|.:.|:.:       .||:||........|:|..      :.:
Human   282 AYPEESPTEPSTKLPGFDSCGKTEIAERKI-------KRIYGGFKSTAGKHPWQASLQSSLPLTI 339

  Fly   143 QRPKGLYWCGGSLISDKHVITAAHCVDMAKRAL-VFLGANEIKNAKEKGQVRLMVPSENFQI--- 203
            ..|:| ::|||:||....|:|||||.|:..|.| |.||..::|  ||:      ...::|::   
Human   340 SMPQG-HFCGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLK--KEE------FHEQSFRVEKI 395

  Fly   204 --YPTWNPKR--LKDDIAIVRLP----HAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYA 260
              |..:|.:.  ..:|||:::|.    |....::.:..:.||...:...|..:    .||||...
Human   396 FKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSGSECH----ISGWGVTE 456

  Fly   261 TG----------VHAISNVL----RYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNARSTCNGDS 311
            ||          |..|:|.|    :.....|.|...|..|..            :..:.||.|||
Human   457 TGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQ------------KPGQDTCQGDS 509

  Fly   312 GGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDW----ISDETG 362
            ||||..::  .....:.||.|:|  ..|.: .|..:|:|..:|:|    |..|:|
Human   510 GGPLTCEK--DGTYYVYGIVSWG--LECGK-RPGVYTQVTKFLNWIKATIKSESG 559

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6592NP_648016.1 Tryp_SPc 122..357 CDD:214473 72/270 (27%)
Tryp_SPc 123..359 CDD:238113 72/271 (27%)
HABP2NP_004123.1 EGF 77..106 CDD:306513
KR 191..277 CDD:238056
Tryp_SPc 314..553 CDD:238113 71/268 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.