Protein Alignment CG6592 and GZMM

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 91/278 - (32%)
• Similarity: 129/278 - (46%)
• Gaps: 54/278 - (19%)

  Fly   112 MLPEGAMAM-----DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMA 171
            :|..||:::     .:|.||....||..||...  ||| .|.:.|||.|:..|.|:|||||:
Human    10 VLALGALSVGSSFGTQIIGGREVIPHSRPYMAS--LQR-NGSHLCGGVLVHPKWVLTAAHCL--- 68

  Fly   172 KRALVFLGANEIKNAKEKGQVRLMV-------PSENFQI-----YPTWNP-KRLKDDIAIVRLPH 223
                          |:...|:||::       |...|.|     :|.:.| ..|::|:|:::|..
Human    69 --------------AQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDG 119

  Fly   224 AVSFNERIHPIQLP-KRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKS-- 285
            .|..:..|.|:.|| ||.......:..:|   |||....| ..:|.|||.:.||::|.|.|.:
Human   120 KVKPSRTIRPLALPSKRQVVAAGTRCSMA---GWGLTHQG-GRLSRVLRELDLQVLDTRMCNNSR 180

  Fly   286 --NFPLSYRGTNICTSGRNA-RSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAF 347
              |..||  .:.:|.:..:. ::.|.||||||||.    .|.|||..:.||.|....|...|...
Human   181 FWNGSLS--PSMVCLAADSKDQAPCKGDSGGPLVC----GKGRVLARVLSFSSRVCTDIFKPPVA 239

  Fly   348 TKVASYLDWISDETGVSA 365
            |.||.|:.||...||.||
Human   240 TAVAPYVSWIRKVTGRSA 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	84/254 (33%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	84/255 (33%)