Protein Alignment CG6592 and GZMB

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_004122.2
• Gene: GZMB / 3002
• HGNCID: 4709
• Length: 247
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 82/264 - (31%)
• Similarity: 124/264 - (46%)
• Gaps: 28/264 - (10%)

  Fly    97 EPLVLNLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHV 161
            :|::|.|...     :||.....  .|.||....||..||...:::...|.|..|||.||.|..|
Human     2 QPILLLLAFL-----LLPRADAG--EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFV 59

  Fly   162 ITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVS 226
            :|||||  ......|.|||:   |.||:...:..:|.:....:|.:|||...:||.:::|.....
Human    60 LTAAHC--WGSSINVTLGAH---NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119

  Fly   227 FNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYA-TGVHAISNVLRYVQLQIIDGRTCKSNFPLS 290
            ....:.|::||....:.:  ..:....:|||:.| .|.|  |:.|:.|::.:.:.|.|:|:....
Human   120 RTRAVQPLRLPSNKAQVK--PGQTCSVAGWGQTAPLGKH--SHTLQEVKMTVQEDRKCESDLRHY 180

  Fly   291 YRGT-NICTSGRNARSTC-NGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASY 353
            |..| .:|......:.|. .||||||||.      .:|..||.|:|...|..   |.|.|||:|:
Human   181 YDSTIELCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYGRNNGMP---PRACTKVSSF 236

  Fly   354 LDWI 357
            :.||
Human   237 VHWI 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	77/238 (32%)
GZMB	NP_004122.2	Tryp_SPc	21..243	CDD:238113	77/238 (32%)