Protein Alignment CG6592 and GZMH

DIOPT Version :9

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_219491.1
• Gene: GZMH / 2999
• HGNCID: 4710
• Length: 246
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 123/263 - (46%)
• Gaps: 27/263 - (10%)

  Fly    97 EPLVLNLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHV 161
            :|.:|      |:..:|..|| ..:.|.||....||..||...:...:.|....|||.|:....|
Human     2 QPFLL------LLAFLLTPGA-GTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFV 59

  Fly   162 ITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVS 226
            :|||||  ......|.|||:   |.||:.:.:..:|.:....:|.:|||...:||.:::|.....
Human    60 LTAAHC--QGSSINVTLGAH---NIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119

  Fly   227 FNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSY 291
            :...:.|::||....:.:  ..:|...:||| |.: :..::..|:.|.|.:.....|:..|..:|
Human   120 WTTAVRPLRLPSSKAQVK--PGQLCSVAGWG-YVS-MSTLATTLQEVLLTVQKDCQCERLFHGNY 180

  Fly   292 -RGTNICTSG-RNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYL 354
             |.|.||... :..::...||||||||.      |.|..||.|:|:..|..   |..:.||:.:|
Human   181 SRATEICVGDPKKTQTGFKGDSGGPLVC------KDVAQGILSYGNKKGTP---PGVYIKVSHFL 236

  Fly   355 DWI 357
            .||
Human   237 PWI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	70/236 (30%)
		Tryp_SPc	123..359	CDD:238113	72/237 (30%)
GZMH	NP_219491.1	Tryp_SPc	21..242	CDD:238113	72/237 (30%)
		Mediates the preference for acidic residues at the P3' and P4' sites	46..48		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1076876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010