Protein Alignment CG6592 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 96/336 - (28%)
• Similarity: 158/336 - (47%)
• Gaps: 50/336 - (14%)

  Fly    37 YLVSMYPGPAGLSTSSSSPFSSSGSLEHDAEMSASNVDNRHIKGLGMGREMSALSEEDDREPLVL 101
            :|.|.:..|:|......||..::.|.:.:|..          |.|...||..|.:|:....||
Human    17 HLYSDHYSPSGRHRLGPSPEPAASSQQAEAVR----------KRLRRRREGGAHAEDCGTAPL-- 69

  Fly   102 NLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGL-YWCGGSLISDKHVITAA 165
                     |.:.:|:    ||.||.......:|:.|.:.::..:.| :.|||:|:.::.|:|||
Human    70 ---------KDVLQGS----RIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAA 121

  Fly   166 HCVDMAKRALVF---LGANEIKNA---KEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHA 224
            ||...|...|::   :|.|.|...   .:|.:::.::      |:|.:..:...:|||:..|..|
Human   122 HCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAII------IHPNFILESYVNDIALFHLKKA 180

  Fly   225 VSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPL 289
            |.:|:.|.||.||...::......|..| |||||.....:| :|:|:..::..|....|.|.  .
Human   181 VRYNDYIQPICLPFDVFQILDGNTKCFI-SGWGRTKEEGNA-TNILQDAEVHYISREMCNSE--R 241

  Fly   290 SYRG----TNICTSGRN-ARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCD-RGYPAAFT 348
            ||.|    |:.|....: |..||.|||||||:......|:..::||||:|  :||. ||:|..:.
Human   242 SYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYG--HGCGRRGFPGVYI 304

  Fly   349 KVASYLDWISD 359
            ..:.|..|:::
Human   305 GPSFYQKWLTE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	77/248 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		5/21 (24%)
		Tryp_SPc	78..316	CDD:238113	77/250 (31%)