Protein Alignment CG6592 and KLK13

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 89/327 - (27%)
• Similarity: 129/327 - (39%)
• Gaps: 95/327 - (29%)

  Fly    90 LSEEDDREPLVLNLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGS 154
            :|:|..:   |||...|   ...||          ||....||..|:|..:|:|   |...|||.
Human    19 VSQESSK---VLNTNGT---SGFLP----------GGYTCFPHSQPWQAALLVQ---GRLLCGGV 64

  Fly   155 LISDKHVITAAHCVDMAKRAL-VFLGANEIKNAKEKGQVRLMV---PSENFQIYPTWNPKRLKDD 215
            |:..|.|:|||||:   |..| |:||.:.:...:...|||.:|   |...::..||    .|..|
Human    65 LVHPKWVLTAAHCL---KEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPT----HLNHD 122

  Fly   216 IAIVRLPHAVSFNERIHPIQ-------LPKRHYEYRSFKNKL-----AIASGWGRYATGVHAISN 268
                   |.:...|...|:|       ||..|      .|:|     ...||||...:.......
Human   123 -------HDIMLLELQSPVQLTGYIQTLPLSH------NNRLTPGTTCRVSGWGTTTSPQVNYPK 174

  Fly   269 VLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGR-NARSTCNGDSGGPLVLQRRHSKKRVLVGITS 332
            .|:...:|:.....|:..:|.......:|...: ..:.:|.||||||||.      .|.|.||.|
Human   175 TLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVC------NRTLYGIVS 233

  Fly   333 FGSIYGC---DRGYPAAFTKVASYLDWISDETGVSAHQDTTEAIFFDQYVREYGKPRQSRRLETE 394
            :|. :.|   ||  |..:|:|:.|:.||.:.                  :|:|         ||:
Human   234 WGD-FPCGQPDR--PGVYTRVSRYVLWIRET------------------IRKY---------ETQ 268

  Fly   395 EQ 396
            :|
Human   269 QQ 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	76/255 (30%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	76/254 (30%)