DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6592 and mst1

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	249	Identity:	71/249 - (28%)
Similarity:	104/249 - (41%)	Gaps:	40/249 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHC-----VDM----AKRALVF 177
            ||.||..||.   |:.|.  |:..||.::|||||:|.:.||:...|     ||:    |....:|
Zfish   481 RIVGGTPGNS---PWTVS--LRDRKGNHFCGGSLVSSEWVISTKQCFSSCYVDLTGYTAMMGTLF 540

  Fly   178 LGANEIKNAKEKGQVRLMV--PSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRH 240
            ....|.:...::..:..:|  |||:              .:.:::|.....||||:..|.||...
Zfish   541 RDPKEGEPDLQRISLTKIVCGPSES--------------HLVMLQLETPAQFNERVSQICLPPER 591

  Fly   241 YEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNAR- 304
            |....  ..:...:|||.  |.......||...|:.::..:.|...|....|...:||....|.
Zfish   592 YIVPD--GTICEIAGWGE--TKGKGDETVLNVAQMPVLSNKDCNQYFKGRVRENEMCTMAFQAGV 652

  Fly   305 STCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWI 357
            ..|..|.||||..|  :|...||.|:..  .:..|.. |.|..|.:|:.|:|||
Zfish   653 GACERDYGGPLACQ--NSDCWVLEGVII--PMRRCGHAGQPNIFIRVSVYVDWI 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	69/247 (28%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	70/248 (28%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056
		Tryp_SPc	481..702	CDD:214473	69/247 (28%)
		Tryp_SPc	482..705	CDD:238113	70/248 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910