Protein Alignment CG6592 and KLK5

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 81/323 - (25%)
• Similarity: 127/323 - (39%)
• Gaps: 76/323 - (23%)

  Fly    61 SLEHDAEM--SASNVDNRHIKGLGMGREMSALSEEDDREPLVLNLETTPLMEKMLPEGAMAMDRI 123
            |.:|.:..  |.||.|      ||.|....|.|::                         :..||
Human    34 SCDHPSNTVPSGSNQD------LGAGAGEDARSDD-------------------------SSSRI 67

  Fly   124 FGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVF---LGANEIKN 185
            ..|...:.|..|:|..:|| ||..|| ||..|:..:.::|||||     |..||   ||...:..
Human    68 INGSDCDMHTQPWQAALLL-RPNQLY-CGAVLVHPQWLLTAAHC-----RKKVFRVRLGHYSLSP 125

  Fly   186 AKEKGQVRLMVPSENFQ-----IYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRS 245
            ..|.||       :.||     .:|.::.....:|:.:::|...:...:.:.||.: ..|.....
Human   126 VYESGQ-------QMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV-SSHCPSAG 182

  Fly   246 FKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNARSTCNGD 310
            .|   .:.||||...:.......||:.:.:.::..:.|:..:|.....|..|...:..|.:|.||
Human   183 TK---CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGD 244

  Fly   311 SGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWISDETGVSAHQDTTEA 372
            ||||:|....      |.|:.|:|. |.|.| ..|..:|.:..:..||         |:|.:|
Human   245 SGGPVVCNGS------LQGLVSWGD-YPCARPNRPGVYTNLCKFTKWI---------QETIQA 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	66/244 (27%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		11/61 (18%)
		Tryp_SPc	66..285	CDD:214473	65/243 (27%)