DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and Plat

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_037283.2	Gene:	Plat / 25692	RGDID:	3342	Length:	559	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	88/361 - (24%)
Similarity:	148/361 - (40%)	Gaps:	69/361 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 YPGPAGLSTSSSS--PFSSSGSLEHDAEMSASNVDNRHIKGLGMGREMSALSEEDDREPL--VLN 102
            |.|....:||.:|  |::|...:........:|     .:.||:||.....:.:.|.:|.  |:.
  Rat   221 YRGTHSFTTSKASCLPWNSMILIGKTYTAWRAN-----SQALGLGRHNYCRNPDGDAKPWCHVMK 280

  Fly   103 --------LETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQR---PKGLYWCGGSLI 156
                    .:.:|.....|.:......||.||...:....|:|..:.::.   |...:.|||.||
  Rat   281 DRKLTWEYCDMSPCSTCGLRQYKQPQFRIKGGLFTDITSHPWQAAIFVKNKRSPGERFLCGGVLI 345

  Fly   157 SDKHVITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPSENFQ--------IYPTWNPKRLK 213
            |...|::||||  ..:|    ...:.:|..  .|:...:||.|..|        ::..::.....
  Rat   346 SSCWVLSAAHC--FVER----FPPHHLKVV--LGRTYRVVPGEEEQTFEIEKYIVHKEFDDDTYD 402

  Fly   214 DDIAIVRL--------PHAVSFNERIHP---IQLPKRHYEYRSFKNKLAIASGWGRYATGVHAIS 267
            :|||:::|        ..:.|......|   :|||    ::...:     .||:|::.......|
  Rat   403 NDIALLQLRSDSSQCAQESSSVGTACLPDPDVQLP----DWTECE-----LSGYGKHEASSPFFS 458

  Fly   268 NVLRYVQLQIIDGRTCKSN--FPLSYRGTNIC-----TSG-RNARSTCNGDSGGPLVLQRRHSKK 324
            :.|:...:::.....|.|.  |..:.....:|     |.| ::....|.||||||||..  ..|:
  Rat   459 DRLKEAHVRLYPSSRCTSQHLFNKTITSNMLCAGDTRTGGNQDVHDACQGDSGGPLVCM--IDKR 521

  Fly   325 RVLVGITSFGSIYGC-DRGYPAAFTKVASYLDWISD 359
            ..|:||.|:|  .|| .:..|..:|||.:||:||.|
  Rat   522 MTLLGIISWG--LGCGQKDVPGIYTKVTNYLNWIQD 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	68/265 (26%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	69/266 (26%)
Plat	NP_037283.2	Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	16/78 (21%)
		Tryp_SPc	311..556	CDD:238113	69/266 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000