DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and CG30091

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	78/292 - (26%)
Similarity:	132/292 - (45%)	Gaps:	46/292 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LGMGREMSALSEEDDREPLVLNLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRP 145
            |..||..:.|.:||...|:           :::|:....:|   .|::.||       .|.|.:.
  Fly    13 LTAGRGSARLLDEDCGVPM-----------QLIPKIVGGVD---AGELKNP-------WMALIKT 56

  Fly   146 KGLYWCGGSLISDKHVITAAHCVDMAKRAL-------VFLGANEIKNAKEKGQVRLMVPSENFQI 203
            ...:.||||:|::|.|:|||||:...:..:       |.||...:....|......:...|...|
  Fly    57 NDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYI 121

  Fly   204 YPTWNPKRLKDDIAIVRLPHAVSFNERIHPI------QLPKRHYEYRSFKNKLAIASGWGRYATG 262
            :.::..:..::|||::||..::.:..:|.|:      ||..:....:.|     .|.|||  .||
  Fly   122 HDSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEF-----TAIGWG--VTG 179

  Fly   263 VHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNARSTCNGDSGGPLVLQRRHS--KKR 325
            ...:||.|:.|::..||.:.|::.|..::.....|......|.||..||||||.:.....  |:.
  Fly   180 NGKMSNNLQMVKIYRIDRKMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRA 244

  Fly   326 VLVGITSFGSIYGCDRGYPAAFTKVASYLDWI 357
            ..:||.|.|: ..| ||: ..:|.|..::|:|
  Fly   245 TQLGIVSTGT-EDC-RGF-GMYTDVMGHIDFI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	68/249 (27%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	69/250 (28%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	69/256 (27%)
		Tryp_SPc	37..276	CDD:238113	70/257 (27%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436440
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940