DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and Hgf

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_058713.1	Gene:	Hgf / 24446	RGDID:	2794	Length:	728	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	70/282 - (24%)
Similarity:	119/282 - (42%)	Gaps:	50/282 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 EDDREPLVLNLETTPLME----KMLPEGAMAMDRIFGGDVGNPHCFPYQ--VG-MLLQRPKGLYW 150
            |.|..|.::||: .|::.    |.|        |:..|       .|.|  || |:..:.:..:.
  Rat   471 EGDTTPTIVNLD-HPVISCAKTKQL--------RVVNG-------IPTQTTVGWMVSLKYRNKHI 519

  Fly   151 CGGSLISDKHVITAAHCVDMAKRAL----VFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKR 211
            ||||||.:..|:||..|.....:.|    .:||.:::....|:.:.:::..|:     ..:.|:
  Rat   520 CGGSLIKESWVLTARQCFPARNKDLKDYEAWLGIHDVHERGEEKRKQILNISQ-----LVYGPE- 578

  Fly   212 LKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQ 276
             ..|:.:::|......:..:..|.||.  |.....:.......|||  .||:.....:||...|.
  Rat   579 -GSDLVLLKLARPAILDNFVSTIDLPS--YGCTIPEKTTCSIYGWG--YTGLINADGLLRVAHLY 638

  Fly   277 IIDGRTCKSNF--PLSYRGTNICTSGRNARS-TCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYG 338
            |:....|..:.  .::...:.:|.......| .|.||.||||:.::.  |.|:::|:...|.  |
  Rat   639 IMGNEKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQH--KMRMVLGVIVPGR--G 699

  Fly   339 C---DRGYPAAFTKVASYLDWI 357
            |   :|  |..|.:||.|..||
  Rat   700 CAIPNR--PGIFVRVAYYAKWI 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	60/247 (24%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	61/248 (25%)
Hgf	NP_058713.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056	70/282 (25%)
		Tryp_SPc	495..719	CDD:214473	60/247 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000