DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and F9

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	246	Identity:	73/246 - (29%)
Similarity:	122/246 - (49%)	Gaps:	19/246 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGAN---EI 183
            |:.||:...|..||:||   :...|...:||||::::|.::||||||:...:..|..|.:   |.
Human   226 RVVGGEDAKPGQFPWQV---VLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEET 287

  Fly   184 KNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKN 248
            ::.::|..|..::|..|:..    ...:...|||::.|...:..|..:.||.:..:.|.....|.
Human   288 EHTEQKRNVIRIIPHHNYNA----AINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKF 348

  Fly   249 KLAIASGWGR-YATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTS-GRNARSTCNGDS 311
            .....||||| :..|..|:  ||:|:::.::|..||..:...:......|.. ....|.:|.|||
Human   349 GSGYVSGWGRVFHKGRSAL--VLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDS 411

  Fly   312 GGPLVLQRRHSKKRVLVGITSFGSIYGCD-RGYPAAFTKVASYLDWISDET 361
            |||.|.:...:.  .|.||.|:|.  .|. :|....:|||:.|::||.::|
Human   412 GGPHVTEVEGTS--FLTGIISWGE--ECAMKGKYGIYTKVSRYVNWIKEKT 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	70/240 (29%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	71/241 (29%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	71/242 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910