DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and Plg

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_032903.3	Gene:	Plg / 18815	MGIID:	97620	Length:	812	Species:	Mus musculus

Alignment Length:	251	Identity:	80/251 - (31%)
Similarity:	128/251 - (50%)	Gaps:	35/251 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRA---LVFLGANE- 182
            |:.||.|.|||.:|:|:. |..|..|.::|||:||:.:.|:|||||::.:.|.   .|.|||:|
Mouse   581 RVVGGCVANPHSWPWQIS-LRTRFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHEE 644

  Fly   183 -IK--NAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYR 244
             |:  :.:|....:|::...|             .|||:::|....:..:::.|..||..:|...
Mouse   645 YIRGLDVQEISVAKLILEPNN-------------RDIALLKLSRPATITDKVIPACLPSPNYMVA 696

  Fly   245 SFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYR--GTNICTSGRNAR--S 305
            .  ..:...:|||. ..|...... |:..||.:|:.:.|.....|:.|  .|.:| :|:.|.  .
Mouse   697 D--RTICYITGWGE-TQGTFGAGR-LKEAQLPVIENKVCNRVEYLNNRVKSTELC-AGQLAGGVD 756

  Fly   306 TCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWISDE 360
            :|.||||||||...:  .|.:|.|:||:|  .||.| ..|..:.:|:.::|||..|
Mouse   757 SCQGDSGGPLVCFEK--DKYILQGVTSWG--LGCARPNKPGVYVRVSRFVDWIERE 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	77/246 (31%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	78/247 (32%)
Plg	NP_032903.3	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		KR	183..262	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		KR	480..562	CDD:214527
		Tryp_SPc	581..805	CDD:214473	77/246 (31%)
		Tryp_SPc	582..807	CDD:238113	78/247 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910