DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and Plat

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_032898.2	Gene:	Plat / 18791	MGIID:	97610	Length:	559	Species:	Mus musculus

Alignment Length:	354	Identity:	90/354 - (25%)
Similarity:	144/354 - (40%)	Gaps:	55/354 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 YPGPAGLSTSSSS--PFSSSGSLEHDAEMSASNVDNRHIKGLGMGREMSALSEEDDREPL--VLN 102
            |.|...|:||.:|  |::|...:........:|     .:.||:||.....:.:.|..|.  |:.
Mouse   221 YRGTHSLTTSQASCLPWNSIVLMGKSYTAWRTN-----SQALGLGRHNYCRNPDGDARPWCHVMK 280

  Fly   103 --------LETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQR---PKGLYWCGGSLI 156
                    .:.:|.....|.:......||.||...:....|:|..:.::.   |...:.|||.||
Mouse   281 DRKLTWEYCDMSPCSTCGLRQYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLI 345

  Fly   157 SDKHVITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPSENFQ--------IYPTWNPKRLK 213
            |...|::||||.      |.....|.:|..  .|:...:||.|..|        ::..::.....
Mouse   346 SSCWVLSAAHCF------LERFPPNHLKVV--LGRTYRVVPGEEEQTFEIEKYIVHEEFDDDTYD 402

  Fly   214 DDIAIVRL----PHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQ 274
            :|||:::|    ......:..:....||..:.:...:..  ...||:|::.......|:.|:...
Mouse   403 NDIALLQLRSQSKQCAQESSSVGTACLPDPNLQLPDWTE--CELSGYGKHEASSPFFSDRLKEAH 465

  Fly   275 LQIIDGRTCKSNFPLSYRGTN--ICT----SGRN--ARSTCNGDSGGPLVLQRRHSKKRVLVGIT 331
            :::.....|.|....:...||  :|.    ||.|  ....|.||||||||..  .:|:..|.||.
Mouse   466 VRLYPSSRCTSQHLFNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGPLVCM--INKQMTLTGII 528

  Fly   332 SFGSIYGC-DRGYPAAFTKVASYLDWISD 359
            |:|  .|| .:..|..:|||.:|||||.|
Mouse   529 SWG--LGCGQKDVPGVYTKVTNYLDWIHD 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	69/258 (27%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	70/259 (27%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	17/78 (22%)
		Tryp_SPc	311..556	CDD:238113	70/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000