Protein Alignment CG6592 and CFD

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 76/260 - (29%)
• Similarity: 114/260 - (43%)
• Gaps: 49/260 - (18%)

  Fly   114 PEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAK--RALV 176
            |.|     ||.||.....|..||...:.|   .|.:.|||.|::::.|::||||::.|.  :..|
Human    29 PRG-----RILGGREAEAHARPYMASVQL---NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQV 85

  Fly   177 FLGANEIKN---AKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPK 238
            .|||:.:..   :|....|...||      :|...|..:..|:.:::|....:....:.|  ||.
Human    86 LLGAHSLSQPEPSKRLYDVLRAVP------HPDSQPDTIDHDLLLLQLSEKATLGPAVRP--LPW 142

  Fly   239 RHYEYRSFKNKLAIASGWGRYATGVHA--ISNVLRYVQLQIIDGRTCKSNFPLSYRGTN------ 295
            :..:.......|...:|||...   ||  ..:.|::|.|.::|..||.       |.|:
Human   143 QRVDRDVAPGTLCDVAGWGIVN---HAGRRPDSLQHVLLPVLDRATCN-------RRTHHDGAIT 197

  Fly   296 ---ICTSGRNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWI 357
               :|... |.|.:|.||||||||.      ..||.|:.:.||....:|..|..:|:||||..||
Human   198 ERLMCAES-NRRDSCKGDSGGPLVC------GGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 255

  Fly   358  357
            Human   256  255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	73/251 (29%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	73/251 (29%)