Protein Alignment CG6592 and Hpn

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001263198.1
• Gene: Hpn / 15451
• MGIID: 1196620
• Length: 445
• Species: Mus musculus
• Alignment Length: 428
• Identity: 116/428 - (27%)
• Similarity: 175/428 - (40%)
• Gaps: 93/428 - (21%)

  Fly     3 KQSASASATLLLLIWL---TWQTMQCIALDWQQVKPMYLVSMYPGPAGLSTSSSSPFSSSGSLEH 64
            |.:|....|||.|..:   :|..:..:....|:  |:|.|.:.||.:.|:....:        |.
Mouse    45 KVAALIVGTLLFLTGIGAASWAIVTILLQSDQE--PLYQVQLSPGDSRLAVFDKT--------EG 99

  Fly    65 DAEMSASNVDNRHIKGLGMGREMSAL-----SEEDDREP--------LVLNLETTPLMEKML--- 113
            ...:..|:..|..:.|||. .||..|     ||.|.|..        ..::....||.:::|
Mouse   100 TWRLLCSSRSNARVAGLGC-EEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVI 163

  Fly   114 -----PEG-------------AMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKH 160
                 |.|             .:.:|||.||...:...:|:||.:   |..|.:.|||||:|...
Mouse   164 SVCDCPRGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSL---RYDGTHLCGGSLLSGDW 225

  Fly   161 VITAAHCVDMAKRAL----VFLG--ANEIKNAKEKGQVRLMVPSENFQIY--PTWNPKRLKDDIA 217
            |:|||||.....|.|    ||.|  |....:|.:.| |:.::....:..:  ||.:..  .:|||
Mouse   226 VLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQLG-VQAVIYHGGYLPFRDPTIDEN--SNDIA 287

  Fly   218 IVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGR---YATGVHAISNVLRYVQLQIID 279
            :|.|..::...|.|.|:.||......  ...|:...:|||.   |  |..|:  ||:..::.||.
Mouse   288 LVHLSSSLPLTEYIQPVCLPAAGQAL--VDGKVCTVTGWGNTQFY--GQQAM--VLQEARVPIIS 346

  Fly   280 GRTCKSNFPLSYRGTNI-----CT----SGRNARSTCNGDSGGPLVLQRRHS--KKRVLVGITSF 333
            ...|.|.   .:.|..|     |.    .|.:|   |.||||||.|.:...|  .:..|.||.|:
Mouse   347 NEVCNSP---DFYGNQIKPKMFCAGYPEGGIDA---CQGDSGGPFVCEDSISGTSRWRLCGIVSW 405

  Fly   334 GSIYGCDRG-YPAAFTKVASYLDWISDETGVSAHQDTT 370
            |:  ||... .|..:|||..:.:||.  ..:..|.:.:
Mouse   406 GT--GCALARKPGVYTKVTDFREWIF--KAIKTHSEAS 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	81/258 (31%)
Hpn	NP_001263198.1	Hepsin-SRCR	79..187	CDD:462736	23/116 (20%)
		Tryp_SPc	191..428	CDD:238113	79/256 (31%)