Protein Alignment CG6592 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 79/262 - (30%)
• Similarity: 128/262 - (48%)
• Gaps: 47/262 - (17%)

  Fly   121 DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKN 185
            ::|..|.......:|:|..|   :.||.::||.||||.:.:::||||  .||:          .|
Human   183 NKIVNGKSSLEGAWPWQASM---QWKGRHYCGASLISSRWLLSAAHC--FAKK----------NN 232

  Fly   186 AKE----------KGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRH 240
            :|:          |..:...|  :|...:..::...|.||||:|:|...|||.|.|..|.||:.
Human   233 SKDWTVNFGIVVNKPYMTRKV--QNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEA- 294

  Fly   241 YEYRSFKNKLAIASGWGR-YATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRG----TNICTSG 300
             :.:..:|...:.:|||. |..|...:  :|:...|:|||.:.|.:::  :|.|    |.:|...
Human   295 -KMKLSENDNVVVTGWGTLYMNGSFPV--ILQEDFLKIIDNKICNASY--AYSGFVTDTMLCAGF 354

  Fly   301 RNARS-TCNGDSGGPLVLQRRHSKKRV--LVGITSFGSIYGC-DRGYPAAFTKVASYLDWISDET 361
            .:..: .|..||||||...   ..:.:  ||||.|:|.  || .:..|..:|:|.||.:||:.:|
Human   355 MSGEADACQNDSGGPLAYP---DSRNIWHLVGIVSWGD--GCGKKNKPGVYTRVTSYRNWITSKT 414

  Fly   362 GV 363
            |:
Human   415 GL 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	77/254 (30%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188
		Tryp_SPc	185..413	CDD:238113	77/255 (30%)