Protein Alignment CG6592 and Cfd

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 256
• Identity: 75/256 - (29%)
• Similarity: 117/256 - (45%)
• Gaps: 33/256 - (12%)

  Fly   117 AMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMA---KRALVFL 178
            |....||.||.....|..||...:   :..|.:.|||:|:.::.|::||||:|..   ....|.|
Mouse    20 AQPRGRILGGQEAAAHARPYMASV---QVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLL 81

  Fly   179 GANEI---KNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRH 240
            ||:.:   :..|....|:.:||      :|...|..|:||:.:.:|....|....:.|:.|   .
Mouse    82 GAHSLSAPEPYKRWYDVQSVVP------HPGSRPDSLEDDLILFKLSQNASLGPHVRPLPL---Q 137

  Fly   241 YEYRSFK-NKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGT---NICTSGR 301
            ||.:..: ..|...:||| ..|......:||..:::.|::..||  |....:.|.   |:..:..
Mouse   138 YEDKEVEPGTLCDVAGWG-VVTHAGRRPDVLHQLRVSIMNRTTC--NLRTYHDGVVTINMMCAES 199

  Fly   302 NARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRG-YPAAFTKVASYLDWISDET 361
            |.|.||.||||.|||.      ...:.|:.::||.. |..| .|..:|:|:||..||.:.|
Mouse   200 NRRDTCRGDSGSPLVC------GDAVEGVVTWGSRV-CGNGKKPGVYTRVSSYRMWIENIT 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	72/246 (29%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	72/247 (29%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)