DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and f7

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	353	Identity:	97/353 - (27%)
Similarity:	153/353 - (43%)	Gaps:	49/353 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 YLVSMYPGPAGLSTSSS------SPFSSSGSLEH-----DAEMSASNVDNRHIKGLGMGREMSAL 90
            |:....||.:|.....|      |....:|..||     |...:.|..|..::...|
Zfish   107 YMCLCAPGFSGRHCEQSIGDVPDSCLHDNGGCEHFCTEQDGRRNCSCADGYYLDNGG-------- 163

  Fly    91 SEEDDREPLVLNLETTPLME--KMLPEGAMAMDRIFGG-DVGNPHCFPYQVGMLLQRPKGLYWCG 152
              :..|...|......||::  |..........||.|| :....|| |:|| :|....||  :||
Zfish   164 --QKCRSHEVFPCGKVPLLQAGKAADHQVDLRSRIVGGSECPKGHC-PWQV-LLKYGEKG--FCG 222

  Fly   153 GSLISDKHVITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIA 217
            |.:.....::|||||::..|...:.:.|.|.....::|..:|:...:.| .:|.:..:....|||
Zfish   223 GVIYKPTWILTAAHCLEKLKVKFLRIVAGEHDLEVDEGTEQLIQVDQMF-THPAYVSETADSDIA 286

  Fly   218 IVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIA----SGWGRYATGVHAISNVLRYVQLQII 278
            ::||...:.::....|:.||.|....|..   .|::    ||||:.:.. ...|.:||.:.:..|
Zfish   287 LLRLRTPIVYSVYAVPVCLPLREMAEREL---WAVSKHTVSGWGKRSED-GPTSRLLRRLLVPRI 347

  Fly   279 DGRTC--KSNFPLSYRGTNICTSG--RNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGC 339
            ..:.|  .||..|:   :|:..:|  ...:.:|.||||||||  .|:.....|:||.|:|.  ||
Zfish   348 RTQECVQVSNLTLT---SNMFCAGYIEGRQDSCKGDSGGPLV--TRYRDTAFLLGIVSWGK--GC 405

  Fly   340 DR-GYPAAFTKVASYLDWISDETGVSAH 366
            .| |....:|:|::||.||...|..:.|
Zfish   406 ARPGSYGIYTRVSNYLQWIRQTTNTTIH 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	75/244 (31%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	76/245 (31%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011	4/13 (31%)
		FXa_inhibition	131..166	CDD:291342	7/44 (16%)
		Tryp_SPc	195..424	CDD:214473	75/244 (31%)
		Tryp_SPc	196..427	CDD:238113	76/246 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000