Protein Alignment CG6592 and KLK8

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 71/246 - (28%)
• Similarity: 108/246 - (43%)
• Gaps: 23/246 - (9%)

  Fly   121 DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKN 185
            |::.||....||..|:|.. |.|..:.|  |||.|:....|:|||||  ...:..|.||.:.::|
Human    76 DKVLGGHECQPHSQPWQAA-LFQGQQLL--CGGVLVGGNWVLTAAHC--KKPKYTVRLGDHSLQN 135

  Fly   186 AKEKGQVRLMVPSENFQIYPTWNPKRLKD---DIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFK 247
               |......:|......:|.:|...::|   |:.:::|....|...::.||.|.    ::.:..
Human   136 ---KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLA----DHCTQP 193

  Fly   248 NKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNARSTCNGDSG 312
            .:....||||...:......:.|...:::|...:.|:..:|.......:|........||.||||
Human   194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSG 258

  Fly   313 GPLVLQRRHSKKRVLVGITSFGSIYGCDRG-YPAAFTKVASYLDWISDETG 362
            ||||..      ..|.||||:|| ..|.|. .|..:|.:..|||||....|
Human   259 GPLVCD------GALQGITSWGS-DPCGRSDKPGVYTNICRYLDWIKKIIG 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	69/239 (29%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	67/238 (28%)