Protein Alignment CG6592 and KLK11

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 82/305 - (26%)
• Similarity: 138/305 - (45%)
• Gaps: 45/305 - (14%)

  Fly    84 GREMSALSEEDDREPLVLNLETTPLMEKMLPEGAMAMD-RIFGGDVGNPHCFPYQVGMLLQRPKG 147
            ||.::|..|...|...:..:....|:...|..|.:..: ||..|....||..|:|.. |.::.:.
Human    14 GRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAA-LFEKTRL 77

  Fly   148 LYWCGGSLISDKHVITAAHCV--------------DMA---------KRALVFLGANEIKNAKEK 189
            |  ||.:||:.:.::|||||:              |::         .|.:|.||.:.::  ||:
Human    78 L--CGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQ--KEE 138

  Fly   190 GQVRLMVPSENFQIYPTWN----PKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKL 250
            |..:....:|:|. :|.:|    .|..::||.:|::...||....:.|:.|..|...    ....
Human   139 GCEQTRTATESFP-HPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT----AGTS 198

  Fly   251 AIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTS-GRNARSTCNGDSGGP 314
            .:.||||..::....:.:.||...:.||:.:.|::.:|.:...|.:|.| ....:.:|.||||||
Human   199 CLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGP 263

  Fly   315 LVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWISD 359
            ||..:.      |.||.|:|.........|..:|||..|:|||.:
Human   264 LVCNQS------LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	73/263 (28%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	72/262 (27%)