Protein Alignment CG6592 and PRSS21

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 78/286 - (27%)
• Similarity: 129/286 - (45%)
• Gaps: 56/286 - (19%)

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYW----CGGSLISDKHVITAAHCVDMAKRALVFLGANE 182
            ||.||:......:|:|..:.|       |    ||.||:|.:..:|||||         |...::
Human    41 RIVGGEDAELGRWPWQGSLRL-------WDSHVCGVSLLSHRWALTAAHC---------FETYSD 89

  Fly   183 IKNAK----EKGQVRLMVPSENFQIYPT--------WNPKRLKD---DIAIVRLPHAVSFNERIH 232
            :.:..    :.||:..|....:.|.|.|        .:|:.|.:   |||:|:|...|::.:.|.
Human    90 LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQ 154

  Fly   233 PIQLPKRHYEYRSFKNKL-AIASGWGRYATGVHAI--SNVLRYVQLQIIDGRTCKSNF-PLSYR- 292
            ||.|....:|   |:|:. ...:||| |.....|:  .:.|:.||:.||:...|...| ..|:|
Human   155 PICLQASTFE---FENRTDCWVTGWG-YIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRK 215

  Fly   293 ---GTNICT-SGRNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVAS 352
               |..:|. :.:..:..|.|||||||...:.....:  :|:.|:|  .||.| ..|..:|.::.
Human   216 DIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQ--IGVVSWG--VGCGRPNRPGVYTNISH 276

  Fly   353 YLDWISD---ETGVSAHQDTTEAIFF 375
            :.:||..   ::|:|....:...:||
Human   277 HFEWIQKLMAQSGMSQPDPSWPLLFF 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	73/264 (28%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	73/264 (28%)