DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and prss12

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_002934300.3	Gene:	prss12 / 100495119	XenbaseID:	XB-GENE-984837	Length:	851	Species:	Xenopus tropicalis

Alignment Length:	365	Identity:	94/365 - (25%)
Similarity:	146/365 - (40%)	Gaps:	75/365 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 YPGPAGLSTSSSSPFSSSGSLEHDAEMSASNVDNRHIKGLGMGREMSALSEED------------ 94
            |.|||...|.:   :...|.       ...:|||  ::..|..|.::...::|
Frog   519 YKGPAKARTMA---YFGEGK-------GPIHVDN--VRCTGYERSLADCIKQDIGTHNCRHSEDA 571

  Fly    95 --------DREPLVLNLETTPL-----MEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQ--R 144
                    .:.....|.|.:||     ::...|:      ||.||.......:|:||.:.|:  .
Frog   572 GVICDYIIKKSTFAANKELSPLVCGSRLQHRRPK------RIIGGKNSVRGGWPWQVALRLKSSH 630

  Fly   145 PKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPSE--------NF 201
            ..|...||.:|||...|:|||||.   ||    .|.|........|....:||.|        ..
Frog   631 GDGRLLCGATLISSCWVLTAAHCF---KR----YGNNTRSYVIRVGDYHTLVPEEYEEDMTIQQI 688

  Fly   202 QIYPTWNPKRLKDDIAIVRL----PHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATG 262
            .|:..:.|.....|||::||    ...|..:..:.|..||.|....:...:...| :|||  .||
Frog   689 IIHNDYRPDGNDYDIALIRLHGTAEQCVQLSTHVLPACLPLRRERPQKTASNCYI-TGWG--DTG 750

  Fly   263 VHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNAR---STCNGDSGGPLVLQRRHSKK 324
             .|.|..|:...:.::..|.|:..:...:.|..:|......:   .:|.||||||||.: |....
Frog   751 -RAYSRTLQQATVTLLPKRVCEERYRSQFTGRMLCAGSVKTQKHVDSCQGDSGGPLVCE-RSGGS 813

  Fly   325 RVLVGITSFGSIYGCD-RGYPAAFTKVASYLDWISDETGV 363
            .::.|:||:|  |||. :..|..:|||::::.||...|.:
Frog   814 WIVYGVTSWG--YGCGVKDSPGVYTKVSAFIPWIKSVTNL 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	74/252 (29%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	75/253 (30%)
prss12	XP_002934300.3	KR	78..140	CDD:412161
		SRCR	148..244	CDD:395421
		SR	257..356	CDD:214555
		SR	363..461	CDD:214555
		SR	476..575	CDD:214555	12/67 (18%)
		Tryp_SPc	607..848	CDD:238113	75/254 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910