Protein Alignment Jon65Ai and PRSS2

DIOPT Version :10

• Sequence 1: NP_648015.1
• Gene: Jon65Ai / 38685
• FlyBaseID: FBgn0035667
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 87/293 - (29%)
• Similarity: 126/293 - (43%)
• Gaps: 75/293 - (25%)

  Fly     1 MKVLAVLLLGVIASATAFEKPVFWKDVPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTW 65
            |.:|.:|.....|.|..|:.              :.:|..||...|..|||.|.|    |.|..:
Human     1 MNLLLILTFVAAAVAAPFDD--------------DDKIVGGYICEENSVPYQVSL----NSGYHF 47

  Fly    66 CGGSIIGNTWVMTAKHCTDGMESVTIYYGAL-----------WRLQAQY-----------THWVG 108
            ||||:|...||::|.||         |..|:           .|:|.:.           ..::.
Human    48 CGGSLISEQWVVSAGHC---------YKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFIN 103

  Fly   109 RSDFIEHG-------SGDISLIR--TPHVDFWSLVNKVELPRYDDRYNNYQGWWALVSGWGKTSD 164
            .:..|.|.       ..||.||:  :|.| ..|.|:.:.||.....    .|..:|:||||.|..
Human   104 AAKIIRHPKYNSRTLDNDILLIKLSSPAV-INSRVSAISLPTAPPA----AGTESLISGWGNTLS 163

  Fly   165 EGGVSEY---LNCVDVQIGENSVCE-NYYGSFSGDLICIPTPE-NKGTCSGDSGGPLVIHDGNRQ 224
            .|  ::|   |.|:|..:...:.|| :|.|..:.::.|:...| .|.:|.|||||| |:.:|..|
Human   164 SG--ADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGP-VVSNGELQ 225

  Fly   225 VGIVSFGSSAGCL-SNGPKGMVRVTSYLDWIRD 256
             ||||:|  .||. .|.|....:|.:|:|||:|
Human   226 -GIVSWG--YGCAQKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_648015.1	Tryp_SPc	37..254	CDD:214473	78/253 (31%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	81/256 (32%)