Protein Alignment Jon65Ai and PRSS1

DIOPT Version :10

• Sequence 1: NP_648015.1
• Gene: Jon65Ai / 38685
• FlyBaseID: FBgn0035667
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 83/281 - (29%)
• Similarity: 121/281 - (43%)
• Gaps: 65/281 - (23%)

  Fly     1 MKVLAVLLLGVIASATAFEKPVFWKDVPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTW 65
            |..|.:|.....|.|..|:.              :.:|..||...|..|||.|.|    |.|..:
Human     1 MNPLLILTFVAAALAAPFDD--------------DDKIVGGYNCEENSVPYQVSL----NSGYHF 47

  Fly    66 CGGSIIGNTWVMTAKHCTDGMESVTIYYGALWRLQAQY-THWV----GRSDFIEHGSGDISLIRT 125
            ||||:|...||::|.||...            |:|.:. .|.:    |...||...    .:||.
Human    48 CGGSLINEQWVVSAGHCYKS------------RIQVRLGEHNIEVLEGNEQFINAA----KIIRH 96

  Fly   126 PHVDFWSLVNKVELPRYDDR-YNNYQ-------------GWWALVSGWGKTSDEGGVSEY---LN 173
            |..|..:|.|.:.|.:...| ..|.:             |...|:||||.|:..|  ::|   |.
Human    97 PQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSG--ADYPDELQ 159

  Fly   174 CVDVQIGENSVCE-NYYGSFSGDLICIPTPE-NKGTCSGDSGGPLVIHDGNRQVGIVSFGSSAGC 236
            |:|..:...:.|| :|.|..:.::.|:...| .|.:|.|||||| |:.:|..| |:||:|.  ||
Human   160 CLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGP-VVCNGQLQ-GVVSWGD--GC 220

  Fly   237 L-SNGPKGMVRVTSYLDWIRD 256
            . .|.|....:|.:|:.||::
Human   221 AQKNKPGVYTKVYNYVKWIKN 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_648015.1	Tryp_SPc	37..254	CDD:214473	75/241 (31%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	75/241 (31%)