DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon65Ai and prss27

DIOPT Version :9

Sequence 1:	NP_001286951.1	Gene:	Jon65Ai / 38685	FlyBaseID:	FBgn0035667	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	90/288 - (31%)
Similarity:	122/288 - (42%)	Gaps:	61/288 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLGVIASATAFEKPVFWKDVPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTWCGGSIIG 72
            |||:...||....|:           :..||..|..|.||:.|:.|..   :|.||.:|||::|.
Frog    15 LLGITPGATDCGIPL-----------VSSRIMGGQSAQEGQWPWQVSF---RNNGGHFCGGTLIS 65

  Fly    73 NTWVMTAKHC---TDGMESVTIYYGALW-------------RLQAQYTHWVGRSDFIEHGSGDIS 121
            ..:|::|.||   :....|||...||..             :....|..:|...|     |||||
Frog    66 KQYVISAAHCFPSSSSASSVTAVLGAYMIDQPDGNQVAIPVQSATNYPSYVNEGD-----SGDIS 125

  Fly   122 LIR--TPHVDFWSLVNKVELPRYDDRYNNYQGWWALVSGWGK-TSDEGGVSEY-LNCVDVQIGEN 182
            |::  :| |.|.:.:..|.||.  |......|....|:|||. .||...||.. |..|.|.:.:.
Frog   126 LVQLASP-VTFTNYILPVCLPA--DTVTFPTGLQCWVTGWGNIASDVSLVSPMTLQEVAVPLIDA 187

  Fly   183 SVCE------NYYGSFS----GDLICIP-TPENKGTCSGDSGGPLVIHDGNR--QVGIVSFGSSA 234
            :.|.      |.||:.|    .|:||.. ....|.:|.||||||||.....:  ..|:||||...
Frog   188 NECNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSSSGQWFLAGVVSFGEGC 252

  Fly   235 GCLSNGPKGMVRVTSYLDWIRDNTGISY 262
            | .:..|.....:.||.|||     :||
Frog   253 G-QAYRPGVYTLMPSYTDWI-----VSY 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_001286951.1	Tryp_SPc	37..254	CDD:214473	80/249 (32%)
Jon65Ai	NP_001286951.1	Tryp_SPc	41..257	CDD:238113	80/248 (32%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	79/248 (32%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910