Protein Alignment Jon65Ai and KLK2

DIOPT Version :10

• Sequence 1: NP_648015.1
• Gene: Jon65Ai / 38685
• FlyBaseID: FBgn0035667
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 69/280 - (24%)
• Similarity: 98/280 - (35%)
• Gaps: 92/280 - (32%)

  Fly    27 VPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTWCGGSIIGNTWVMTAKHCTDGMESVTI 91
            ||:    |:.||..|:...:...|:.|.:   .:.|...|||.::...||:||.||
Human    18 VPL----IQSRIVGGWECEKHSQPWQVAV---YSHGWAHCGGVLVHPQWVLTAAHC--------- 66

  Fly    92 YYGALWRLQAQYTHWVGRSDFI---------------------------------EHGSGDISLI 123
                   |:.....|:||.:..                                 |..|.|:.|:
Human    67 -------LKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLL 124

  Fly   124 R-TPHVDFWSLVNKVELPRYDDRYNNYQGWWALVSGWGKTSDEGGVSEY-----LNCVDVQIGEN 182
            | :.......:|..:.||..:...    |.....||||....|    |:     |.||.:.:..|
Human   125 RLSEPAKITDVVKVLGLPTQEPAL----GTTCYASGWGSIEPE----EFLRPRSLQCVSLHLLSN 181

  Fly   183 SVCENYY-----------GSFSGDLICIPTPENKGTCSGDSGGPLVIHDGNRQVGIVSFGSSAGC 236
            .:|...|           |.::|         .|.||.||||||||. :|..| ||.|:|.....
Human   182 DMCARAYSEKVTEFMLCAGLWTG---------GKDTCGGDSGGPLVC-NGVLQ-GITSWGPEPCA 235

  Fly   237 LSNGPKGMVRVTSYLDWIRD 256
            |...|....:|..|..||:|
Human   236 LPEKPAVYTKVVHYRKWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_648015.1	Tryp_SPc	37..254	CDD:214473	63/266 (24%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	65/269 (24%)