DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon65Ai and C1s2

DIOPT Version :9

Sequence 1:	NP_001286951.1	Gene:	Jon65Ai / 38685	FlyBaseID:	FBgn0035667	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	279	Identity:	72/279 - (25%)
Similarity:	108/279 - (38%)	Gaps:	67/279 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTWCGGSIIGNTWVMTAKHCTDGMESVTI 91
            ||.....::.:|..|.||.....|:.|......      .||::|...||:||.|..:.....::
Mouse   433 VPTEPFQVQQKIFGGQPAKIENFPWQVFFNHPT------AGGALINEYWVLTAAHVVEKNSDPSM 491

  Fly    92 YYGA-------LWRLQAQYTHWV-------------GRSDFIEHGSGDISLIRTPH-VDFWSLVN 135
            |.|.       |...|..||..|             .|::|    ..||:|::... |......:
Mouse   492 YAGITALRLADLENAQRLYTKRVIIHPGWKEDDDLNPRTNF----DNDIALVQLKDPVKMGPKFS 552

  Fly   136 KVELPRYDDRYNNYQGWWALVSGWGKTSD-------EGG---VSEYLNCVDVQIGENSVC--ENY 188
            .:.||.....||...|...|:||||:|..       .|.   |:....|..|: .||...  |:|
Mouse   553 PICLPGTSSEYNLSPGDMGLISGWGRTEKRLHVINLRGAKVPVTSLETCKQVK-EENPTARPEDY 616

  Fly   189 YGSFSGDLICIPTPENKG--TCSGDSGGPLVIHDGNRQ------VGIVSFGSSAGCLSNGPKGM- 244
            .  .:.::||   ...||  :|.|||||.......|.:      .|:||:|...|..     |:
Mouse   617 V--ITDNMIC---AGEKGVDSCKGDSGGAFAFQVPNVKAPKFYVAGLVSWGKKCGAY-----GVY 671

  Fly   245 VRVTSYLDWI----RDNTG 259
            .:|.:|:|||    ::|:|
Mouse   672 TKVKNYVDWILKTMQENSG 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_001286951.1	Tryp_SPc	37..254	CDD:214473	66/258 (26%)
Jon65Ai	NP_001286951.1	Tryp_SPc	41..257	CDD:238113	67/261 (26%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	66/258 (26%)
		Tryp_SPc	444..684	CDD:238113	68/260 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000