DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon65Ai and F9

DIOPT Version :9

Sequence 1:	NP_001286951.1	Gene:	Jon65Ai / 38685	FlyBaseID:	FBgn0035667	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	256	Identity:	66/256 - (25%)
Similarity:	112/256 - (43%)	Gaps:	51/256 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RITMGYPAYEGKVPYIVGLGFSKNGG-GTWCGGSIIGNTWVMTAKHCTDGMESVTIYYGALWRLQ 100
            |:..|..|..|:.|:.|.|    ||. ..:|||||:...|::||.||.:....:|:..|
Human   226 RVVGGEDAKPGQFPWQVVL----NGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAG------ 280

  Fly   101 AQYTHWVGRSDFIEHGSGDISLIRTPHVDFWSLVNK-------VELPR-------------YDDR 145
               .|.:..::..|.....|.:|  ||.::.:.:||       :||..             .|..
Human   281 ---EHNIEETEHTEQKRNVIRII--PHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKE 340

  Fly   146 YNNY-----QGWWALVSGWGKTSDEGGVSEYLNCVDVQIGENSVC-ENYYGSFSGDLICIPTPE- 203
            |.|.     .|:   |||||:...:|..:..|..:.|.:.:.:.| .:...:...::.|....|
Human   341 YTNIFLKFGSGY---VSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEG 402

  Fly   204 NKGTCSGDSGGPLV--IHDGNRQVGIVSFGSSAGCLSNGPKGM-VRVTSYLDWIRDNTGIS 261
            .:.:|.||||||.|  :...:...||:|:|..  |...|..|: .:|:.|::||::.|.::
Human   403 GRDSCQGDSGGPHVTEVEGTSFLTGIISWGEE--CAMKGKYGIYTKVSRYVNWIKEKTKLT 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_001286951.1	Tryp_SPc	37..254	CDD:214473	63/247 (26%)
Jon65Ai	NP_001286951.1	Tryp_SPc	41..257	CDD:238113	64/246 (26%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	64/249 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910