Protein Alignment Jon65Ai and Ctsg

DIOPT Version :10

• Sequence 1: NP_648015.1
• Gene: Jon65Ai / 38685
• FlyBaseID: FBgn0035667
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_031826.1
• Gene: Ctsg / 13035
• MGIID: 88563
• Length: 261
• Species: Mus musculus
• Alignment Length: 234
• Identity: 69/234 - (29%)
• Similarity: 103/234 - (44%)
• Gaps: 27/234 - (11%)

  Fly    36 GRITMGYPAYEGKVPYIVGLGFSKNGGGTWCGGSIIGNTWVMTAKHCTDGMESVTI-YYGALWRL 99
            |:|..|..|.....||:..|......|.:.|||.::...:|:||.||.....:||: .:....|.
Mouse    19 GKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRE 83

  Fly   100 QAQYTHWVGRSDFIEHGSGDISLIRTPHVDFWSL-----------VNKVELPRYDDRYNNYQGWW 153
            :.|....|.|:  |.|...:...||.   |...|           |..|.||:...:..  .|..
Mouse    84 RTQQLITVLRA--IRHPDYNPQNIRN---DIMLLQLRRRARRSGSVKPVALPQASKKLQ--PGDL 141

  Fly   154 ALVSGWGKTSDEGGVSEYLNCVDVQIGENSVCENYYGSFSGDL-ICIPTP-ENKGTCSGDSGGPL 216
            ..|:|||:.|...| :..|..|.:::..:.:|.|.:..::... ||:..| |.|....|||||||
Mouse   142 CTVAGWGRVSQSRG-TNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPL 205

  Fly   217 VIHDGNRQVGIVSFGSSAGCLSNGPKGMVRVTSYLDWIR 255
            |.  .|...||||:||:.|   |.|....::.|::.||:
Mouse   206 VC--SNVAQGIVSYGSNNG---NPPAVFTKIQSFMPWIK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Ai	NP_648015.1	Tryp_SPc	37..254	CDD:214473	66/230 (29%)
Ctsg	NP_031826.1	Tryp_SPc	21..241	CDD:238113	68/232 (29%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	21..25		1/3 (33%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	97..111		4/16 (25%)