DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon65Aii and C1s1

DIOPT Version :9

Sequence 1:	NP_648014.1	Gene:	Jon65Aii / 38684	FlyBaseID:	FBgn0035666	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	274	Identity:	76/274 - (27%)
Similarity:	106/274 - (38%)	Gaps:	56/274 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LERPVPVKDMPAGN-KINGRITNGYPAYEGKVPYIVALRFDNGNGGGWYCGGSIIGHEWVLTAAH 81
            |.|.:|...:|... :::.||..|.||.....|:.|.......:       |::|...|||||||
Mouse   424 LPRCIPACGVPTEPFQVHQRIFGGQPAKIENFPWQVFFNHPRAS-------GALINEYWVLTAAH 481

  Fly    82 CTYGAS----YV-TISYGAVWRQQPQ-------FTH---------YDTGNLHNDIALIRTPH-VD 124
            .....|    || |:|......:..|       |.|         ....|..|||||::... |.
Mouse   482 VLEKISDPLMYVGTMSVRTTLLENAQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDPVK 546

  Fly   125 FWSLVNKVELPRYDDRYNNFYGWWALLSGWGSSSD----------SSGMTDYLNCVDIQISDNSV 179
            ....|:.:.||.....||...|...|:|||||:..          ...:|....|..::..:.:|
Mouse   547 MGPKVSPICLPGTSSEYNVSPGDMGLISGWGSTEKKVFVINLRGAKVPVTSLETCKQVKEENPTV 611

  Fly   180 CLDYYGSHYITSNHLCYATPENKGSCSGDSGGPLVLHDGNRQV------GIVSFGSAAGCLSNSP 238
            ..:.|   ..|.|.:| |..:...||.|||||.......|..|      |:||:|...|..
Mouse   612 RPEDY---VFTDNMIC-AGEKGVDSCHGDSGGAFAFQVPNVTVPKFYVAGLVSWGKRCGTY---- 668

  Fly   239 KGL-TRVTGYLDWI 251
             |: |:|..|:|||
Mouse   669 -GVYTKVKNYVDWI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aii	NP_648014.1	Tryp_SPc	36..251	CDD:214473	70/253 (28%)
Jon65Aii	NP_648014.1	Tryp_SPc	37..254	CDD:238113	71/254 (28%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056	2/3 (67%)
		Tryp_SPc	443..681	CDD:214473	70/253 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000