Protein Alignment Jon65Aiii and KLK4

DIOPT Version :10

• Sequence 1: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 67/241 - (27%)
• Similarity: 107/241 - (44%)
• Gaps: 22/241 - (9%)

  Fly    39 RITNGKTATSGQFPYQVGLSFASTSGSWWCGGSIIDNTWVLTAAHCTSGASAVTIYYG-----AT 98
            :|.||:..:....|:|..|..   ....:|.|.::...|||:||||..  ::.||..|     |.
Human    30 QIINGEDCSPHSQPWQAALVM---ENELFCSGVLVHPQWVLSAAHCFQ--NSYTIGLGLHSLEAD 89

  Fly    99 VRTSAQLVQTVSADNFVQHASYNSIVLRNDISLIK-TPTVAFTALINKVELPAIAGTYSTYTGQQ 162
            ....:|:|:   |...|:|..||..:|.||:.||| ..:|:.:..|..:.:.:...|    .|..
Human    90 QEPGSQMVE---ASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT----AGNS 147

  Fly   163 AIASGWGKTSDSATSVANTLQYEVFEVVSVSQCQNTYGSLVATNNVICVATPNKVSTCNGDSGGP 227
            .:.||||..::.  .:...||.....|||...|...|..|...:........::..:||||||||
Human   148 CLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGP 210

  Fly   228 LVLVSDSKLIGVTSFVSSAGCESGAPAGFTRVTSYLDWIKTNTGVS 273
              |:.:..|.|:.||..:...:.|.|..:|.:..:.:||:.....|
Human   211 --LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	64/232 (28%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	66/234 (28%)