Protein Alignment Jon65Aiii and PRSS2

DIOPT Version :10

• Sequence 1: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 87/284 - (30%)
• Similarity: 131/284 - (46%)
• Gaps: 47/284 - (16%)

  Fly     1 MKVLVVFALALATASAGLLPQQVPIHPRDLPAVTNIEGRITNGKTATSGQFPYQVGLSFASTSGS 65
            |.:|::.....|..:|       |....|         :|..|........||||.|:    ||.
Human     1 MNLLLILTFVAAAVAA-------PFDDDD---------KIVGGYICEENSVPYQVSLN----SGY 45

  Fly    66 WWCGGSIIDNTWVLTAAHCTSGASAVTI------YYGATVRTSAQLV-------QTVSADNFVQH 117
            .:||||:|...||::|.||...|....:      |:...||.....:       |.::|...::|
Human    46 HFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRH 110

  Fly   118 ASYNSIVLRNDISLIK--TPTVAFTALINKVELPAIAGTYSTYTGQQAIASGWGKTSDSATSVAN 180
            ..|||..|.|||.|||  :|.| ..:.::.:.||    |.....|.:::.||||.|..|.....:
Human   111 PKYNSRTLDNDILLIKLSSPAV-INSRVSAISLP----TAPPAAGTESLISGWGNTLSSGADYPD 170

  Fly   181 TLQYEVFEVVSVSQCQNTYGSLVATNNVICVA-TPNKVSTCNGDSGGPLVLVSDSKLIGVTSFVS 244
            .||.....|:|.::|:.:|...: |||:.||. ......:|.||||||  :||:.:|.|:.|:
Human   171 ELQCLDAPVLSQAECEASYPGKI-TNNMFCVGFLEGGKDSCQGDSGGP--VVSNGELQGIVSW-- 230

  Fly   245 SAGC-ESGAPAGFTRVTSYLDWIK 267
            ..|| :...|..:|:|.:|:||||
Human   231 GYGCAQKNRPGVYTKVYNYVDWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	78/243 (32%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	81/245 (33%)