Protein Alignment Jon65Aiii and KLK12

DIOPT Version :10

• Sequence 1: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 72/229 - (31%)
• Similarity: 102/229 - (44%)
• Gaps: 23/229 - (10%)

  Fly    39 RITNGKTATSGQFPYQVGLSFASTSGSWWCGGSIIDNTWVLTAAHCTSGASAVTIYYGATVRTSA 103
            :|.||........|:|||| |..|  |..|||.:||:.||||||||:  .|...:..|....:..
Human    21 KIFNGTECGRNSQPWQVGL-FEGT--SLRCGGVLIDHRWVLTAAHCS--GSRYWVRLGEHSLSQL 80

  Fly   104 QLVQTVSADNF-VQHASY--NSIVLRNDISLIKTP-TVAFTALINKVELP---AIAGTYSTYTGQ 161
            ...:.:....| |.|..|  .|....:|:.|::.. .|..|:.:..:.||   |.|||
Human    81 DWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT------- 138

  Fly   162 QAIASGWGKTSDSATSVANTLQYEVFEVVSVSQCQNTYGSLVATNNVICVATPNKVSTCNGDSGG 226
            :...||||.|:.......:.||.....:||.:.|...|...: |:|::|.........|.|||||
Human   139 ECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI-TSNMVCAGGVPGQDACQGDSGG 202

  Fly   227 PLVLVSDSKLIGVTSFVSSAGC-ESGAPAGFTRV 259
            |  ||....|.|:.|:.|...| :.|.|..:|.:
Human   203 P--LVCGGVLQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	72/229 (31%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	72/228 (32%)