Protein Alignment Jon65Aiii and KLK2

DIOPT Version :10

• Sequence 1: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 80/279 - (28%)
• Similarity: 111/279 - (39%)
• Gaps: 44/279 - (15%)

  Fly     5 VVFALALATASAGLLPQQVPIHPRDLPAVTNIEGRITNGKTATSGQFPYQVGLSFASTSGSW-WC 68
            :|.::||:....|.:|.              |:.||..|........|:||    |..|..| .|
Human     4 LVLSIALSVGCTGAVPL--------------IQSRIVGGWECEKHSQPWQV----AVYSHGWAHC 50

  Fly    69 GGSIIDNTWVLTAAHCTSGASAVTIYYGA-TVRTSAQLVQTVSADNFVQHASYNSIVLR------ 126
            ||.::...||||||||....|.|  :.|. .:.......|.|...:...|..||..:|:
Human    51 GGVLVHPQWVLTAAHCLKKNSQV--WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRP 113

  Fly   127 -----NDISLIKTPTVA-FTALINKVELPAIAGTYSTYTGQQAIASGWGKTSDSATSVANTLQYE 185
                 :|:.|::....| .|.::..:.||    |.....|....|||||...........:||..
Human   114 DEDSSHDLMLLRLSEPAKITDVVKVLGLP----TQEPALGTTCYASGWGSIEPEEFLRPRSLQCV 174

  Fly   186 VFEVVSVSQCQNTYGSLVATNNVICVA--TPNKVSTCNGDSGGPLVLVSDSKLIGVTSFVSSAGC 248
            ...::|...|...|...| |..::|..  |..| .||.||||||  ||.:..|.|:||:......
Human   175 SLHLLSNDMCARAYSEKV-TEFMLCAGLWTGGK-DTCGGDSGGP--LVCNGVLQGITSWGPEPCA 235

  Fly   249 ESGAPAGFTRVTSYLDWIK 267
            ....||.:|:|..|..|||
Human   236 LPEKPAVYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	71/242 (29%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	73/244 (30%)