Protein Alignment Jon65Aiii and KLK3

DIOPT Version :10

• Sequence 1: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 80/281 - (28%)
• Similarity: 110/281 - (39%)
• Gaps: 41/281 - (14%)

  Fly     1 MKVLVVFALALATASAGLLPQQVPIHPRDLPAVTNIEGRITNGKTATSGQFPYQVGLSFASTSGS 65
            |.|.||| |.|:....|..|.              |..||..|........|:||   ..::.|.
Human     1 MWVPVVF-LTLSVTWIGAAPL--------------ILSRIVGGWECEKHSQPWQV---LVASRGR 47

  Fly    66 WWCGGSIIDNTWVLTAAHCTSGASAVTIYYGATVRTSAQLVQTVSADNFVQHASYNSIVLRN--- 127
            ..|||.::...||||||||....|.:.:...:..... ...|.....:...|..|:..:|:|
Human    48 AVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFL 111

  Fly   128 --------DISLIKTPTVA-FTALINKVELPAIAGTYSTYTGQQAIASGWGKTSDSATSVANTLQ 183
                    |:.|::....| .|..:..::||    |.....|....|||||............||
Human   112 RPGDDSSHDLMLLRLSEPAELTDAVKVMDLP----TQEPALGTTCYASGWGSIEPEEFLTPKKLQ 172

  Fly   184 YEVFEVVSVSQCQNTYGSLVATNNVICVA--TPNKVSTCNGDSGGPLVLVSDSKLIGVTSFVSSA 246
            .....|:|...|...:...| |..::|..  |..| |||:||||||  ||.:..|.|:||:.|..
Human   173 CVDLHVISNDVCAQVHPQKV-TKFMLCAGRWTGGK-STCSGDSGGP--LVCNGVLQGITSWGSEP 233

  Fly   247 GCESGAPAGFTRVTSYLDWIK 267
            ......|:.:|:|..|..|||
Human   234 CALPERPSLYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	67/240 (28%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	69/242 (29%)