DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon65Aiii and prss60.3

DIOPT Version :9

Sequence 1:	NP_648013.1	Gene:	Jon65Aiii / 38683	FlyBaseID:	FBgn0035665	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	290	Identity:	101/290 - (34%)
Similarity:	138/290 - (47%)	Gaps:	34/290 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKV--LVVFALALATASAGLLPQ-----QVPIHPRDLPAVTNIEGRITNGKTATSGQFPYQVGLS 58
            ||:  |....|.|.....|.|.|     |.|::.           ||..|..|:.|.:|:||.|
Zfish     1 MKMWRLTCATLTLLICVKGSLSQLNVCGQAPLNT-----------RIVGGVNASPGSWPWQVSL- 53

  Fly    59 FASTSGSWWCGGSIIDNTWVLTAAHCTSGASAVT--IYYGATVRTSAQLVQTVS--ADNFVQHAS 119
            .:...|..:||||:|.:.||||||||.||.|..|  :|.|...:....:.:|..  |.:|| |:|
Zfish    54 HSPKYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVVYLGRRTQQGINIYETSRNVAKSFV-HSS 117

  Fly   120 YNSIVLRNDISLIK-TPTVAFTALINKVELPAIAGTYSTYTGQQAIASGWGKTSDSATSVA-NTL 182
            |||....|||:|:: :..|.||..|..|.|.|....||  .|..:..:|||.........| ..|
Zfish   118 YNSNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNSVYS--AGTSSWITGWGDIQAGVNLPAPGIL 180

  Fly   183 QYEVFEVVSVSQCQNTYGSLVATNNVICVA-TPNKVSTCNGDSGGPLV--LVSDSKLIGVTSFVS 244
            |..:..||:..:|....||...|||:||.. |.....||.||||||:|  |.:.....|:||:
Zfish   181 QETMIPVVANDRCNALLGSGTVTNNMICAGLTQGGKDTCQGDSGGPMVTRLCTVWVQAGITSW-- 243

  Fly   245 SAGC-ESGAPAGFTRVTSYLDWIKTNTGVS 273
            ..|| :..:|..:|||:.|..||.:...::
Zfish   244 GYGCADPNSPGVYTRVSQYQSWISSKISLN 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	89/236 (38%)
Jon65Aiii	NP_648013.1	Tryp_SPc	40..269	CDD:238113	90/238 (38%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	90/238 (38%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000