DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon65Aiii and C1s2

DIOPT Version :9

Sequence 1:	NP_648013.1	Gene:	Jon65Aiii / 38683	FlyBaseID:	FBgn0035665	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	280	Identity:	80/280 - (28%)
Similarity:	120/280 - (42%)	Gaps:	49/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PRDLPAV------TNIEGRITNGKTATSGQFPYQVGLSFASTSGSWWCGGSIIDNTWVLTAAHCT 85
            ||.:|..      ..::.:|..|:.|....||:||..:..:      .||::|:..|||||||..
Mouse   425 PRCIPVCGVPTEPFQVQQKIFGGQPAKIENFPWQVFFNHPT------AGGALINEYWVLTAAHVV 483

  Fly    86 SGASAVTIYYGATVRTSAQL--VQTVSADNFVQHASYNS-------IVLRNDISLI--KTPTVAF 139
            ...|..::|.|.|....|.|  .|.:.....:.|..:..       ....|||:|:  |.| |..
Mouse   484 EKNSDPSMYAGITALRLADLENAQRLYTKRVIIHPGWKEDDDLNPRTNFDNDIALVQLKDP-VKM 547

  Fly   140 TALINKVELPAIAGTYSTYTGQQAIASGWGKTSDSATSVANTLQYEVFEVVSVSQCQNTY----- 199
            ....:.:.||..:..|:...|...:.||||:| :....|.| |:.....|.|:..|:...
Mouse   548 GPKFSPICLPGTSSEYNLSPGDMGLISGWGRT-EKRLHVIN-LRGAKVPVTSLETCKQVKEENPT 610

  Fly   200 ---GSLVATNNVICVATPNKVSTCNGDSGG------PLVLVSDSKLIGVTSFVSSAGCESGAPAG 255
               ...|.|:|:|| |....|.:|.|||||      |.|......:.|:.|:    |.:.||...
Mouse   611 ARPEDYVITDNMIC-AGEKGVDSCKGDSGGAFAFQVPNVKAPKFYVAGLVSW----GKKCGAYGV 670

  Fly   256 FTRVTSYLDWI-KT---NTG 271
            :|:|.:|:||| ||   |:|
Mouse   671 YTKVKNYVDWILKTMQENSG 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	71/251 (28%)
Jon65Aiii	NP_648013.1	Tryp_SPc	40..269	CDD:238113	75/257 (29%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056	2/2 (100%)
		Tryp_SPc	443..681	CDD:214473	71/251 (28%)
		Tryp_SPc	444..684	CDD:238113	73/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000