Protein Alignment CG6462 and KLK4

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 79/273 - (28%)
• Similarity: 125/273 - (45%)
• Gaps: 41/273 - (15%)

  Fly    49 WQLGYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITL 113
            |.|||       ....:.|:..:...::|..||..:....|:|..||::    :.:.|.|.|:..
Human    10 WFLGY-------LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVME----NELFCSGVLVHP 63

  Fly   114 QFVLTAAHCLTDAIAAKIYTGA----TVFADVEDSVE----ELQVTHRDFIIYPDYLGFGGYSDL 170
            |:||:||||..::     ||..    ::.||.|...:    .|.|.|      |:|......:||
Human    64 QWVLSAAHCFQNS-----YTIGLGLHSLEADQEPGSQMVEASLSVRH------PEYNRPLLANDL 117

  Fly   171 ALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQE 235
            .||:|...|..|:.::.|.:|.    |....|....:||||.|.:.  :...:||.::..|:.:|
Human   118 MLIKLDESVSESDTIRSISIAS----QCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEE 176

  Fly   236 RCICYFLPGLVSQRRHLCTDGSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTV 300
            .|...:.| |..........|.:.:.:||||||||::.:    .||.|:.|||.|...:||.|.|
Human   177 VCSKLYDP-LYHPSMFCAGGGQDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGV 236

  Fly   301 YTRITAYLPWIRQ 313
            ||.:..:..||.:
Human   237 YTNLCKFTEWIEK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	74/245 (30%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	74/245 (30%)