Protein Alignment CG6462 and PRSS27

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 86/275 - (31%)
• Similarity: 121/275 - (44%)
• Gaps: 44/275 - (16%)

  Fly    67 GNQTAAVRT---------RIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHC 122
            |:|.|...|         |:.||:....|.:|:||.  ||.:|:..  ||||||..|:|||||||
Human    16 GSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVS--IQRNGSHF--CGGSLIAEQWVLTAAHC 76

  Fly   123 LTDAIAAKIY---TGATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQ 184
            ..:.....:|   .||...  |:.....:....|.....|.|.|....:|:||:.|...|..:..
Human    77 FRNTSETSLYQVLLGARQL--VQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNY 139

  Fly   185 VQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTD--KRTRLLQYLDAEVIDQERC-ICY------ 240
            :.|:.|....:  .|..|....::|||...:. |  ...|:||.|...:||..:| :.|
Human   140 ILPVCLPDPSV--IFETGMNCWVTGWGSPSEE-DLLPEPRILQKLAVPIIDTPKCNLLYSKDTEF 201

  Fly   241 -FLPGLVSQRRHLCTDGSNG-RGACNGDSGGPVV----YHWRNVSYLIGVTSFGSAEGC-EVGGP 298
             :.|..: :...||.....| :.||.||||||:|    ..|...    ||.|:|  ||| ....|
Human   202 GYQPKTI-KNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQA----GVISWG--EGCARQNRP 259

  Fly   299 TVYTRITAYLPWIRQ 313
            .||.|:||:..||.:
Human   260 GVYIRVTAHHNWIHR 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	81/256 (32%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	81/255 (32%)