Protein Alignment CG6462 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 84/289 - (29%)
• Similarity: 127/289 - (43%)
• Gaps: 48/289 - (16%)

  Fly    45 MERRWQ-----LGYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLV 104
            :|..||     ...:...|||.:.   |.:..|  :||.||:....|.:|:|..:.:.....
Human   186 LEEAWQPRNNCTSGQVVSLRCSEC---GARPLA--SRIVGGQSVAPGRWPWQASVALGFRHT--- 242

  Fly   105 KCGGSLITLQFVLTAAHCLTDAIAA-----KIYTGATVFADVEDS----VEELQVTHRDFIIYPD 160
             ||||::..::|:|||||:.....|     :::.|....:.|...    ||.:       |.:|.
Human   243 -CGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVERI-------IPHPL 299

  Fly   161 YLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQ 225
            |.......|:||:||...:..|:.|..:.|..:  .|:|..|....:||||:...|....:.:||
Human   300 YSAQNHDYDVALLRLQTALNFSDTVGAVCLPAK--EQHFPKGSRCWVSGWGHTHPSHTYSSDMLQ 362

  Fly   226 YLDAEVIDQERC--ICYFLPGLVSQRRHLCTDGSNGRG-ACNGDSGGPVVY----HWRNVSYLIG 283
            .....:...:.|  .|.:...|..  |.||....:||. ||.||||||:|.    .||    |:|
Human   363 DTVVPLFSTQLCNSSCVYSGALTP--RMLCAGYLDGRADACQGDSGGPLVCPDGDTWR----LVG 421

  Fly   284 VTSFGSAEGC-EVGGPTVYTRITAYLPWI 311
            |.|:|  .|| |...|.||.::..:|.||
Human   422 VVSWG--RGCAEPNHPGVYAKVAEFLDWI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	75/252 (30%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	7/29 (24%)
		Tryp_SPc	217..448	CDD:214473	74/251 (29%)