DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and prss60.1

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	253	Identity:	84/253 - (33%)
Similarity:	117/253 - (46%)	Gaps:	28/253 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAK--IYT 133
            |.:..||.||..|..|.:|:||.|...:.|...  ||||||..::||||||||.....:.  ::.
Zfish    28 APLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHF--CGGSLINSEWVLTAAHCLPRITTSSLLVFL 90

  Fly   134 GATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQN 198
            |.|....|  :..|:..|.....::|.|......:|:||:.|...|..|..::|:.||.:  :..
Zfish    91 GKTTQQGV--NTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCLAAQ--NSV 151

  Fly   199 FLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCI-------CYFLPGLVSQRRHLCTDG 256
            |..|....::|||.:        :|...|.|..|.||..|       |..|.|..|...::...|
Zfish   152 FPNGTSSWITGWGNI--------QLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMICAG 208

  Fly   257 --SNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWI 311
              ..||..|.||||||:|.....|....|:||:|  .|| :...|.||||::.|..||
Zfish   209 LLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWG--YGCADPYSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	81/246 (33%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	82/247 (33%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	81/246 (33%)
		Tryp_SPc	34..267	CDD:238113	82/247 (33%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587862
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940