Protein Alignment CG6462 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 83/270 - (30%)
• Similarity: 119/270 - (44%)
• Gaps: 56/270 - (20%)

  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVK-CGGSLITLQFVLTAAHCLTDAIAAKIYTG 134
            |..|..|.||:.|.|..:|:||.|  ::.|...:. ||||||..|:|||||||
Human    25 ALQRVGIVGGQEAPRSKWPWQVSL--RVHGPYWMHFCGGSLIHPQWVLTAAHC------------ 75

  Fly   135 ATVFADVED------SVEELQVTHRD-------FIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQ 186
              |..||:|      .:.|..:.::|       .|::|.:......:|:||:.|...|..|..|.
Human    76 --VGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVH 138

  Fly   187 PIEL--AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRL-----LQYLDAEVIDQERCICYFLPG 244
            .:.|  |.|    .|..|....::|||    ..|...||     |:.:...:::...|...:..|
Human   139 TVTLPPASE----TFPPGMPCWVTGWG----DVDNDERLPPPFPLKQVKVPIMENHICDAKYHLG 195

  Fly   245 L-------VSQRRHLCTDGSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVY 301
            .       :.:...||. |:..|.:|.||||||:|..........||.|:|  ||| :...|.:|
Human   196 AYTGDDVRIVRDDMLCA-GNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIY 257

  Fly   302 TRITAYLPWI 311
            ||:|.||.||
Human   258 TRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	81/264 (31%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	81/264 (31%)