Protein Alignment CG6462 and Tmprss6

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_082178.2
• Gene: Tmprss6 / 71753
• MGIID: 1919003
• Length: 811
• Species: Mus musculus
• Alignment Length: 275
• Identity: 83/275 - (30%)
• Similarity: 127/275 - (46%)
• Gaps: 77/275 - (28%)

  Fly    75 TRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCL-TDAIAA-KIYTGATV 137
            :||.||.:::.|.:|:|..|  |:.|..:  |||:||..::|:|||||. .|::|: |::   ||
Mouse   575 SRIVGGTVSSEGEWPWQASL--QIRGRHI--CGGALIADRWVITAAHCFQEDSMASPKLW---TV 632

  Fly   138 F-----------ADVEDSVEELQVTHRDFIIYP-------DYLGFGGYSDLALIRLPRKVRTSEQ 184
            |           .:|...|..|       .::|       ||       |:||::|...|..|..
Mouse   633 FLGKMRQNSRWPGEVSFKVSRL-------FLHPYHEEDSHDY-------DVALLQLDHPVVYSAT 683

  Fly   185 VQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQR 249
            |:|:.|...  ...|..|:...::|||...:. ...:..||.:|.:::.|:.|         |:.
Mouse   684 VRPVCLPAR--SHFFEPGQHCWITGWGAQREG-GPVSNTLQKVDVQLVPQDLC---------SEA 736

  Fly   250 -------RHLCTDGSNG-RGACNGDSGGPVVY-----HWRNVSYLIGVTSFGSAEGCEVGGPT-- 299
                   |.||.....| :.||.||||||:|.     .|    :|.|:.|:|.  ||  |.|.
Mouse   737 YRYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRW----FLAGLVSWGL--GC--GRPNFF 793

  Fly   300 -VYTRITAYLPWIRQ 313
             ||||:|..:.||:|
Mouse   794 GVYTRVTRVINWIQQ 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	82/273 (30%)
Tmprss6	NP_082178.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		SEA	88..182	CDD:460188
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:395011
		Tryp_SPc	577..809	CDD:238113	82/273 (30%)