DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and f9b

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	267	Identity:	80/267 - (29%)
Similarity:	128/267 - (47%)	Gaps:	41/267 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 NQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIY 132
            |.|...:.||.||:.|..|..|:||..:.:::  .:|.|||||::.::|:|||||:...
Zfish   247 NNTTNNKYRIVGGDEAIPGEIPWQVVFLEKVN--KIVFCGGSLLSEEWVITAAHCVEGK------ 303

  Fly   133 TGATVFADVEDSVEELQVTHRD-----FIIYPDYLGFGG-YS-DLALIRLPRKVRTSEQVQPIEL 190
            .|:......|..|.:::.|..|     :.|:|.|..... |: |:||::|.:.|...:...||.|
Zfish   304 QGSFFIRVGEHDVSKMEGTESDHGIEEYHIHPRYNSQRSLYNHDIALLKLKKPVILFDYAVPICL 368

  Fly   191 AGEFMHQNFLVGKVVTL-SGWG---YLGDSTDKRTRLLQYLDAEVIDQERC-------ICYFLPG 244
            ..:...:|.|.....:| ||||   |.|..::    :||.::...:|:.:|       |..|:
Zfish   369 GSKDFTENLLQSAENSLVSGWGRLRYGGIESN----VLQKVELPYVDRIKCKGSSTDSISRFM-- 427

  Fly   245 LVSQRRHLCTDGSNGR-GACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYL 308
                   .|...|..| .||.||||||....:::..:|.|:.|:|. |..:.|...:||||:.|:
Zfish   428 -------FCAGYSTVRKDACQGDSGGPHATRYKDTWFLTGIVSWGE-ECAKEGKYGIYTRISKYM 484

  Fly   309 PWIRQQT 315
            .||...|
Zfish   485 AWITNIT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	75/253 (30%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	76/255 (30%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342
		Tryp_SPc	255..487	CDD:214473	75/253 (30%)
		Tryp_SPc	256..490	CDD:238113	76/255 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000