Protein Alignment CG6462 and PRSS56

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 84/267 - (31%)
• Similarity: 118/267 - (44%)
• Gaps: 34/267 - (12%)

  Fly    61 EKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTD 125
            |:.....|.|.| ..||.||..|..|.:|:.|.|  ||.|..|  |||.|:...:|||||||...
Human    90 ERRPSTANVTRA-HGRIVGGSAAPPGAWPWLVRL--QLGGQPL--CGGVLVAASWVLTAAHCFVG 149

  Fly   126 AIAAKIYTGATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIEL 190
            |....::|.........:..||:.|..  .:.:|.:.....::||||::|...|......:|:.|
Human   150 APNELLWTVTLAEGSRGEQAEEVPVNR--ILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCL 212

  Fly   191 AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQER--------CICYFLPGLVS 247
            ..|  .|....|....::|||.|.:...         :||.:.:.|        |.....||| .
Human   213 PQE--PQEPPAGTACAIAGWGALFEDGP---------EAEAVREARVPLLSTDTCRRALGPGL-R 265

  Fly   248 QRRHLCTDG-SNGRGACNGDSGGPVVYHW---RNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAY 307
            ....||... :.|..:|.||||||:....   |....|.||||:|  :|| |.|.|.||||:..:
Human   266 PSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWG--DGCGEPGKPGVYTRVAVF 328

  Fly   308 LPWIRQQ 314
            ..|:::|
Human   329 KDWLQEQ 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	78/249 (31%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	78/249 (31%)
		PksD	<178..600	CDD:442550	51/172 (30%)