Protein Alignment CG6462 and PRSS22

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 79/250 - (31%)
• Similarity: 120/250 - (48%)
• Gaps: 23/250 - (9%)

  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAI----AAKIYTGAT 136
            |:.|||.:|...:|:.|.  ||.:|..  .|.|||:|.::|:|||||..|.:    ...:..||.
Human   157 RVVGGEDSTDSEWPWIVS--IQKNGTH--HCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAW 217

  Fly   137 VFADVEDSVEELQVTHRDFIIYPDY-LGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFL 200
            ...:.....:::.|...:  .:|.| ...|..:|:||:||.|.::.||:|.||.|....:|  ..
Human   218 QLGNPGSRSQKVGVAWVE--PHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIH--LP 278

  Fly   201 VGKVVTLSGWGYLGDSTD-KRTRLLQYLDAEVIDQERCICYFLPGL----VSQRRHLCTDGSNG- 259
            ......:||||.:.|... ...:.||.|...:||.|.|...:..|.    :::.. ||.....|
Human   279 PNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDM-LCAGYLEGE 342

  Fly   260 RGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQ 313
            |.||.||||||::........|.|:.|:|  ||| |...|.||..::|:..|:.:
Human   343 RDACLGDSGGPLMCQVDGAWLLAGIISWG--EGCAERNRPGVYISLSAHRSWVEK 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	78/248 (31%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	78/248 (31%)