Protein Alignment CG6462 and F12

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_067464.2
• Gene: F12 / 58992
• MGIID: 1891012
• Length: 597
• Species: Mus musculus
• Alignment Length: 315
• Identity: 87/315 - (27%)
• Similarity: 132/315 - (41%)
• Gaps: 63/315 - (20%)

  Fly    29 TFEHPKEETPDDDDAIME-------RRWQLGYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRG 86
            :..|...::.|...::.:       :|::.|..:|                  .|:.||.:|..|
Mouse   318 SLSHAPNDSTDHQTSLSKTNTMGCGQRFRKGLSSF------------------MRVVGGLVALPG 364

  Fly    87 MFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFADVEDSVEELQ-V 150
            ..||...|   ..|.:.  |.||||...:||||||||.:..|.:..|..........|.|..| :
Mouse   365 SHPYIAAL---YWGNNF--CAGSLIAPCWVLTAAHCLQNRPAPEELTVVLGQDRHNQSCEWCQTL 424

  Fly   151 THRDFIIYPDYLGFGGYSDLALIRLPRKVRT------SEQVQPIELAGEFMHQNFLVGKVVTLSG 209
            ..|.:.::..:.......||||:|| ::.:|      |..|||:.|.......:..|  :..::|
Mouse   425 AVRSYRLHEGFSSITYQHDLALLRL-QESKTNSCAILSPHVQPVCLPSGAAPPSETV--LCEVAG 486

  Fly   210 WGYLGDSTDKRTRLLQYLDAEVIDQERCI------CYFLPGLVSQRRHLCT---DGSNGRGACNG 265
            ||:..:..::.:..||......|..:||.      ...|||:      ||.   :|  |..||.|
Mouse   487 WGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHGDAILPGM------LCAGFLEG--GTDACQG 543

  Fly   266 DSGGPVVYHWRNVSY---LIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQQTA 316
            |||||:|.......:   |.||.|:||  || :...|.|||.:..||.||::..|
Mouse   544 DSGGPLVCEEGTAEHQLTLRGVISWGS--GCGDRNKPGVYTDVANYLAWIQKHIA 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	80/256 (31%)
F12	NP_067464.2	FN2	41..88	CDD:238019
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		KR	217..295	CDD:412161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..338		2/19 (11%)
		Tryp_SPc	355..594	CDD:238113	80/256 (31%)