DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6462 and Hgfac

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_445772.1	Gene:	Hgfac / 58947	RGDID:	70909	Length:	653	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	94/331 - (28%)
Similarity:	136/331 - (41%)	Gaps:	68/331 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 HPKEETPDDDDAIMERRW-------QLGYENFRL-RCEKFEM-------------EGNQTAA--- 72
            |.....||.|    ||.|       .|.:|..|| .||....             |...||.
  Rat   332 HAYCRNPDKD----ERPWCYVVKDSALSWEYCRLAACESLARVHSRIPEVLATLPESTSTARPTC 392

  Fly    73 ---------VRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLT---- 124
                     :|.||.||..:..|..|:...:.|   |...  |.|||:...:|::||||.:
  Rat   393 GKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI---GNGF--CAGSLVHTCWVVSAAHCFSSSPP 452

  Fly   125 -DAIAAKIYTGATVFADVEDSVEELQVTHRDFIIYPDYLGFG-GYSDLALIRLPRK-----VRTS 182
             |:|.  :..|...|....|..:...:  ..::.|..|..|. ...||.||||.:|     || |
  Rat   453 RDSIT--VVLGQHFFNRTTDVTQTFAI--EKYVPYTLYSVFNPNDHDLVLIRLKKKGERCAVR-S 512

  Fly   183 EQVQPIEL--AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGL 245
            :.||||.|  ||    .:|..|....::|||::.::....:..|......::...:|....:.|.
  Rat   513 QFVQPICLPEAG----SSFPTGHKCQIAGWGHMDENVSGYSNSLLEALVPLVADHKCSSPEVYGA 573

  Fly   246 VSQRRHLCTDGSNGRG-ACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYL 308
            ......||....:.:. ||.||||||:|.....|:||.|:.|:|  :|| .:..|.||||::.|:
  Rat   574 DISPNMLCAGYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWG--DGCGRLNKPGVYTRVSNYV 636

  Fly   309 PWIRQQ 314
            .||..:
  Rat   637 DWINDR 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	75/249 (30%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	76/251 (30%)
Hgfac	NP_445772.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF	242..274	CDD:278437
		Kringle	283..364	CDD:278480	11/35 (31%)
		Tryp_SPc	405..639	CDD:214473	75/249 (30%)
		Tryp_SPc	406..641	CDD:238113	76/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000