Protein Alignment CG6462 and KLK6

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 73/249 - (29%)
• Similarity: 109/249 - (43%)
• Gaps: 31/249 - (12%)

  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGA 135
            |..:.::..|....:...|||..|  ..||..|  |||.||...:|||||||....:  :::.|.
Human    16 AEEQNKLVHGGPCDKTSHPYQAAL--YTSGHLL--CGGVLIHPLWVLTAAHCKKPNL--QVFLGK 74

  Fly   136 TVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGE------F 194
            ......|.|.|:..|...  :|:|||.......|:.|:||.|..:.||.:||:.|..:      .
Human    75 HNLRQRESSQEQSSVVRA--VIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTS 137

  Fly   195 MHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNG 259
            .|          :.|||...|.....|....|:  .::.:|.|. :..||.::|......|...|
Human   138 CH----------ILGWGKTADGDFPDTIQCAYI--HLVSREECE-HAYPGQITQNMLCAGDEKYG 189

  Fly   260 RGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQ 313
            :.:|.||||||:|..    .:|.|:.|:|:........|.|||.:..|..||::
Human   190 KDSCQGDSGGPLVCG----DHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	72/243 (30%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	70/238 (29%)